Morphology Core Facility

The Morphology Core Facility provides instrumentation and technical expertise for the preparation, acquisition and analysis of images of cells and tissues at the light microscopic level. Given the cost of such instrumentation and the high level of technical expertise required to perform these investigational techniques, this Core was established to ensure the availability of these techniques for Center members. In recognition of the broad usefulness of this Core facility, the School of Medicine has partnered with the Liver Center by making ongoing, major investments to ensure that the facility remains state-of-the-art.

Specific Activities and Services Available

  • Confocal Microscopy
  • Epifluorescence Microscopy including quantitative and ratio imaging
  • Cryosectioning
  • Multiphoton Microscopy
  • Time Lapse Microscopy and Image Processing & Analysis
  • Super-resolution Microscopy

Equipment

  • NEW: Leica Gated STED super-resolution microscope
  • Zeiss LSM 710 duo combined confocal and multiphoton microscope
  • Leica SP5 confocal microscope
  • Nikon E900 epifluorescence microscope
  • Olympus BX51 multi-headed brightfield microscope
  • Zeiss Discovery 8 SteReo dissecting microscope
  • NEW: Leica CM 1860 Cryostat
  • NEW: Olympus CK41

For training and access to this equipment, please contact Al Mennone.

<<Cellular and Molecular Physiology Core Facility   Clinical Translation Facility>>

Morphology Core Director

Michael Harris Nathanson, MD, PhD

Gladys Phillips Crofoot Professor of Medicine (Digestive Diseases) and Professor of Cell Biology

Contact Info

michael.nathanson@yale.edu